Articles
Our works are below. * means Corresponding author.
発行年 | タイトル | 著者 | 詳細 |
---|---|---|---|
2018 | Glucuronylated core 1 glycans are required for precise localization of neuromuscular junctions and normal formation of basement membranes on Drosophila muscles. | Itoh, K., Akimoto, Y., Kondo. S., Ichimiya, T., Aoki, K., Tiemeyer. M., Nishihara. S.* | Dev Biol. 436, 108-124 (2018). |
2018 | O-GlcNAc on PKCζ inhibits the FGF4-PKCζ-MEK-ERK1/2 pathway via inhibition of PKCζ phosphorylation in mouse embryonic stem cells. | Miura, T., Kume, M., Kawamura, T., Yamamoto, K., Hamakubo, T., Nishihara, S.* | Stem Cell Reports, 10, 1–15 (2018). |
2017 | Strong radioprotective FGF1 signaling down-regulates proliferative and metastatic capabilities of the angiosarcoma cell line, ISOS-1, through the dual inhibition of EGFR and VEGFR pathways. | Miura, T., Fujita, M., Kawano, M., Imadome, K., Yasuda,T., Nishihara, S., Imamura, T., Masuzawa, M., Imai, T., Nakayama, F. | Clin Transl Radiat Oncol. 7, 83-90 (2017). |
2017 | Short stop mediates axonal compartmentalization of mucin-type core 1 glycans. | Kinoshita, T., Sato, C., Fuwa, T.J., Nishihara, S.* | Sci Rep., 7, 41455 (2017). |
2016 | O-GlcNAc is required for the survival of primed pluripotent stem cells and their reversion to the naïve state. | Miura, T., Nishihara, S.* | BBRC, 480, 655-661 (2016). |
2016 | Mucin-type core 1 glycans regulate the localization of neuromuscular junctions and establishment of muscle cell architecture in Drosophila. | Itoh, K., Akimoto, Y., Fuwa, T.J., Sato, C., Komatsu, A., Nishihara, S.* | Dev Biol., 412, 114-127 (2016). |
2016 | Atmospheric-pressure plasma-irradiation inhibits mouse embryonic stem cell differentiation to mesoderm and endoderm but promotes ectoderm differentiation. | Miura, T., Hamaguchi, S., Nishihara, S.* | J. Phys. D: Appl. Phys., 49, 165401-1 - 165401-12 (2016). |
2015 | Preparation of a polyclonal antibody that recognizes a unique galactoseβ1-4fucose disaccharide epitope. | Takeuchi, T., Nishiyama, K., Saito, S., Tamura, M., Fuwa, T.J., Nishihara, S., Takahashi, H., Natsugari, H,. Arata, Y., Kasai, K. | Carbohydr Res. 412, 50-55 (2015). |
2015 | Identification of β1,3-galactosyltransferases responsible for biosynthesis of insect complex-type N-glycans containing a T-antigen unit in the honeybee. | Ichimiya, T., Maeda, M., Sakamura, S., Kanazawa, M., Nishihara, S.*, Kimura, Y. | Glycoconjugate J., 32, 141-151 (2015). |
2015 | Phenotype-based clustering of glycosylation-related genes by RNAimediated gene silencing. | Yamamoto-Hino, M., Yoshida, H., Ichimiya, T., Sakamura, S., Maeda, M., Kimura, Y., Sasaki, N., Aoki-Kinoshita, K.F., Kinoshita-Toyoda, A., Toyoda, H., Ueda, R., Nishihara, S.*, Goto, S. | Genes to Cells, 20, 521-542 (2015). |
2015 | Reduction of T antigen causes loss of hematopoietic progenitors in Drosophila through the inhibition of filopodial extensions from the hematopoietic niche. | Fuwa, T.J., Kinoshita, T., Nishida, H., Nishihara, S.* | Dev Biol., 401, 206-219 (2015). |
2014 | A chicken influenza virus recognizes fucosylated α2,3 sialoglycan receptors on the epithelial cells lining upper respiratory tracts of chickens. | Hiono, T., Okamatsu, M., Nishihara, S., Takase-Yoden, S., Sakoda, Y., Kida, H. | Virology, 456–457, 131–138 (2014). |
2014 | Proliferation assay of mouse embryonic stem (ES) cells exposed to atmosphericpressure plasmas at room temperature. | Miura, T., Ando, A., Hirano, K., Ogura, C., Kanazawa, T., Ikeguchi, M., Seki, A., Nishihara, S., Hamaguchi, S. | J. Phys. D: Appl. Phys. 47(44) 445402-1 - 445402-12 (2014). |
2014 | Electron microscopy of primary cell cultures in solution and correlative optical microscopy using ASEM. | Hirano, K., Kinoshita, T., Uemura, T., Motohashi, H., Watanabe, Y., Ebihara, T., Nishiyama, H., Sato, M., Suga, M., Maruyama, Y., Tsuji, N.M., Yamamoto, M., Nishihara, S.* , Sato, C. | Ultramicroscopy,143, 52-66 (2014). |
2014 | Immuno-electron microscopy of primary cell cultures from genetically modified animals in liquid by atmospheric scanning electron microscopy. | Kinoshita, T., Mori, Y., Hirano, K., Sugimoto, S., Okuda, K., Matsumoto, S., Namiki, T., Ebihara, T., Kawata, M., Nishiyama, H., Sato, M., Suga, M., Higashiyama, K., Sonomoto, K., Mizunoe, Y., Nishihara, S.*, Sato, C. | Microsc Microanal, 20, 470-484 (2014). |
2014 | Frequent glycan structure mining of influenza virus data revealed a sulfated glycan motif that increased viral infection. | Ichimiya, T., Nishihara, S., Takase-Yoden, S., Kida, H., Aoki- Kinoshita, K.F. | Bioinformatics, 30, 706-711(2014). |
2013 | The transition of mouse pluripotent stem cells from the naïve to the primed state requires Fas signaling through 3-O sulfated heparan sulfate structures recognized by the HS4C3 antibody. | Hirano, K., Van Kuppevelt, T.H., Nishihara, S.* | BBRC, 430, 1175–1181 (2013). |
2013 | Sulfation of keratan sulfate proteoglycan reduces radiation-induced apoptosis in human Burkitt's lymphoma cell lines. | Nakayama, F., Umeda, S., Ichimiya, T., Kamiyama, S., Hazawa, M., Yasuda, T., Nishihara, S., Imai, T. | FEBS Lett., 587, 231-783 (2013). |
2012 | 3-O-sulfated heparan sulfate recognized by the antibody HS4C3 contribute to the differentiation of mouse embryonic stem cells via Fas signaling. | Hirano, K., Sasaki, N., Ichimiya, T., Miura , T., Van Kuppevelt ,T.H., Nishihara, S.* | PLoS One, 7, e43440 (2012). |
2012 | O-sulfate groups of heparin are critical for inhibition of ecotropic murine leukemia virus infection by heparin. | Seki, Y., Mizukura, M., Ichimiya, T., Suda, Y., Nishihara, S., Masuda, M., Takase-Yoden, S. | Virology, 424, 56-66 (2012). |
2011 | LacdiNAc (GalNAcβ1-4GlcNAc) contributes to self-renewal of mouse embryonic stem cells by regulating LIF/STAT3 signaling. | Sasaki, N., Shinomi, M., Hirano, K., Ui-Tei, K., Nishihara, S.* | Stem Cells, 29, 641-650 (2011). |
2011 | Expression and role of 3'-phosphoadenosine 5'-phosphosulfate transporters in human colorectal carcinoma. | Kamiyama, S., Ichimiya, T., Ikehara, Y., Takase, T., Fujimoto, I., Suda, T., Nakamori, S., Nakamura, M., Nakayama, F., Irimura, T., Nakanishi, H., Watanabe, M., Narimatsu, H., Nishihara, S.* | Glycobiology, 21, 235-246 (2011). |
2010 | Identification of genes required for neural-specific glycosylation using functional genomics. | Yamamoto-Hino, M., Kanie, Y., Awano, W., Aoki-Kinoshita, K.F., Yano, H., Nishihara, S., Okano, H., Ueda, R., Kanie, O., Goto, S. | PLoS Genet., 6, e1001254 (2010). |
2010 | Chemical inhibition of sulfation accelerates neural differentiation of mouse embryonic stem cells and human induced pluripotent stem cells. | Sasaki, N., Hirano, T., Kobayashi, K., Toyoda, M., Miyakawa, Y., Okita, H., Kiyokawa, N., Akutsu, H., Umezawa, A., Nishihara, S.* | BBRC, 401, 480-486 (2010). |
2010 | Increased apoptosis of myoblasts in Drosophila model for the Walker-Warburg syndrome. | Ueyama, M., Akimoto, Y., Ichimiya, T., Ueda, R., Kawakami, H., Aigaki, T., Nishihara, S.* | PLoS One, 5, e11557 (2010). |
2010 | Two Golgi-resident 3' -phosphoadenosine 5' -phosphosulfate transporters play distinct roles in heparan sulfate modifications and embryonic and larval development in Caenorhabditis elegans. | Dejima, K., Murata, D., Mizuguchi, S., Nomura, K.H., Izumikawa, T., Kitagawa, H., Gengyo-Ando, K., Yoshina, S., Ichimiya, T., Nishihara, S., Mitani, S., Nomura, K. | J Biol Chem., 285, 24717-24728 (2010). |
2010 | Two pathways for importing GDP-fucose into the endoplasmic reticulum lumen function redundantly in the O-fucosylation of Notch in Drosophila. | Ishikawa, H.O., Ayukawa, T., Nakayama, M., Higashi, S., Kamiyama, S., Nishihara, S., Aoki, K., Ishida, N., Sanai, Y., Matsuno, K. | J Biol Chem., 285, 4122-4129 (2010). |
2009 | The 3'-phosphoadenosine 5'-phosphosulfate transporters, PAPST1 and 2, contribute to the maintenance and differentiation of mouse embryonic stem cells. | Sasaki, N., Hirano, T., Ichimiya, T., Wakao, M., Hirano, K., Kinoshita-Toyoda, A., Toyoda, H., Suda, Y., Nishihara, S.* | PLoS One, 4, e8262 (2009). |
2009 | The ortholog of human solute carrier family 35 member B1 (UDP-galactose transporter-related protein 1) is involved in maintenance of ER homeostasis and essential for larval development in Caenorhabditis elegans. | Dejima, K., Murata, D., Mizuguchi, S., Nomura, K.H. Gengyo-Ando, K., Mitani, S., Kamiyama, S., Nishihara, S., Nomura, K. | FASEB J., 23, 2215-2225 (2009). |
2009 | ER/Golgi nucleotide sugar transporters contribute to the cellular release of UDP-sugar signaling molecules. | Sesma. J.I., Esther, C.R. Jr, Kreda, S.M., Jones, L., O'Neal, W., Nishihara, S., Nicholas, R.A., Lazarowski, E.R. | J. Biol. Chem., 284, 12572-12583 (2009). |
2009 | Insight into the regulation of glycan synthesis in Drosophila chaoptin based on mass spectrometry. | Kanie, Y., Yamamoto-Hino, M., Karino, Y., Yokozawa, H., Nishihara, S., Ueda, R., Goto, S., Kanie, O. | PLoS ONE, 4, e5434 (2009). |
2008 | Identification of the Drosophila core 1 β1,3-galactosyltransferase gene that synthesizes T antigen in the embryonic central nervous system and hemocytes. | Yoshida, H., Fuwa, T.J., Arima, M., Hamamoto, H., Sasaki, N., Ichimiya, T., Osawa, K., Ueda, R., Nishihara, S.* | Glycobiology, 18, 1094-1104 (2008). |
2008 | Sequential glycosyltransfer reactions on a microfluidic device: Synthesis of a glycosaminoglycan linkage region tetrasaccharide. | Ono, Y., Kitajima, M., Daikoku, S., Shiroya, T., Nishihara, S., Kanie, Y., Suzuki, K., Goto, S., Kanie, O. | Lab. on a Chip, 8, 2168-2173 (2008). |
2008 | Functional analysis of proteoglycan galactosyltransferase II RNAi mutant flies. | Ueyama, M., Takemae, H., Ohmae, Y., Yoshida, H., Toyoda, H., Ueda, R., Nishihara, S.* | J. Biol. Chem., 283, 6076-6084 (2008). |
2008 | Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells. | Sasaki, N., Okishio, K., Ui-Tei, K., Saigo, K., Kinoshita-Toyoda, A., Toyoda, H., Nishimura, T., Suda, Y., Hayasaka, M., Hanaoka, K., Hitoshi, S., Ikenaka, K., Nishihara, S.* | J. Biol. Chem., 283, 3594-3606 (2008). |
2007 | Drosophila β1,4-N-acetylgalactosaminyltransferase-A synthesizes the LacdiNAc structures on several glycoproteins and glycosphingolipids. | Biochem Biophys Res Commun, 354, 522-527 (2007). | Sasaki, N., Yoshida, H., Fuwa, T.J., Kinoshita-Toyoda, A., Toyoda, H., Hirabayashi, Y., Ishida, H., Ueda, R., Nishihara, S.* |
2007 | Mice lacking α1,3-fucosyltransferase IX demonstrate disappearance of Lewis x structure in brain and increased anxiety-like behaviors. | Kudo, T., Fujii, T., Ikegami, S., Inokuchi, K., Takayama,Y., Ikehara, Y., Nishihara, S., Togayachi, A., Takahashi, S., Tachibana, K., Yuasa, S., Narimatsu, H. | Glycobiology, 17, 1-9 (2007). |
2006 | Involvement of Drosophila Sir2-like genes in the regulation of life span. | Kusama, S., Ueda, R., Suda, T., Nishihara, S., Etsuko, T. | Genes & Genetic Systems, 81, 341-348 (2006). |
2006 | Identification and characterization of a novel Drosophila 3'-phosphoadenosine 5'-phosphosulfate transporter. | Goda, E., Kamiyama, S., Uno, T., Yoshida, H., Ueyama, M., Kinoshita-Toyoda , A., Toyoda, H., Ueda, R., Nishihara, S.* | J Biol Chem, 281, 28508-28517 (2006). |
2006 | Molecular cloning and characterization of a novel 3'-phosphoadenosine 5'-phosphosulfate transporter, PAPST2. | Kamiyama, S., Sasaki, N., Goda, E., Ui-Tei, K., Saigo, K., Narimatsu, H., Jigami, Y., Kannagi, R., Irimura, T., Nishihara, S.* | J Biol Chem, 281, 10945-10953 (2006). |
2005 | β4GalT-II is a key regulator of glycosylation of the proteins involved in neuronal development. | Sasaki, N., Manya, H., Okubo, R., Kobayashi, K., Ishidad,H., Toda, T., Endo, T., Nishihara, S.* | Biochem Biophys Res Commun, 333, 131-137 (2005). |
2004 | The twisted abdomen phenotype of Drosophila POMT1 and POMT2 mutants coincides with their heterophilic protein O-mannosyltransferase activity. | Ichimiya, T., Manya, H., Ohmae, Y., Yoshida, H., Takahashi, K., Ueda, R., Endo, T., Nishihara, S.*: | J Biol Chem, 279, 42638-42647 (2004). |
2004 | Drosophila glucosylceramide synthase: A negative regulator of cell death mediated by proapoptotic factors. | Kohyama-Koganeya, A., Sasamura, T., Oshima, E., Suzuki, E., Nishihara, S., Ueda, R., Hirabayashi Y. | J Biol Chem, 279, 35995-6002 (2004). |
2004 | Molecular cloning and characterization of a human multi-substrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection. | Suda,T., Kamiyama, S., Suzuki. M., Kikuchi N., Nakayama., Narimatsu H., Jigami , Y., Aoki, T., Nishihara, S.*: | J Biol Chem, 279, 26469-26474 (2004). |
2004 | Normal embryonic and germ cell development in mice lacking α1,3-fucosyltransferase IX (Fut9) which show disappearance of stage-specific embryonic antigen 1. | Kudo, T., Kaneko, M., Iwasaki, H., Togayachi, A., Nishihara, S., Abe, K., Narimatsu. H. | Mol Cell Biol, 24, 4221-4228(2004). |
2004 | Design and synthesis of peptide mimetics of GDP-Fucose: Targeting Inhibitors of fucosyltransferases. | Tanaka, T, Tsuda, C., Miura, T., Inazu, T., Tsuji, S., Nishihara, S., Hisamatsu, M., Kajimoto, T. | Synlett, 2004, 243-246 (2004). |
2003 | Molecular cloning and identification of 3'-phosphoadenosine 5'-phosphosulfate transporter. | Kamiyama, S., Suda, T., Ueda, R., Suzuki, M., Okubo, R., Kikuchi, N., Chiba, Y., Goto, S., Toyoda, H., Saigo, K., Watanabe, M., Narimatsu, H., Jigami, Y., Nishihara, S.* | J Biol Chem, 278, 25958-25963 (2003). |
2003 | Proteoglycan UDP-galactose: β-xylose β1,4galactosyltransferase I is essential for viability in Drosophila Melanogaster | Takemae, H., Ueda, R., Ohkubo, R., Nakato, H., Izumi, S., Saigo, K., Nishihara, S.* | J Biol Chem, 278, 15571-15578 (2003). |